Glucosamine is an effective chondroprotective agent, although its action in osteoarthritis is slow. On the other hand, Methylsulfonylmethane (MSM) is an effective analgesic and natural anti-inflammatory. In a study of 118 patients with mild or moderate osteoarthritis for 12 weeks, participants were randomly given the following treatments three times a day: 500 mg of glucosamine, 500 mg of MSM, 500 mg of glucosamine + 500 mg of MSM, placebo capsules
In the study it was observed that the combined glucosamine + MSM therapy was more effective in reducing pain and inflammation and in improving the functional capacity of the joints. The analgesic and anti-inflammatory activity of this combination was also faster than in the individual treatments, and did not present problems of intolerance (as in any of the other treatments).
Reference: Clin Drug Invest 2004; 24 (6): 353-363 Study available in our technical department.