Combined use of Glucosamine and Methylsulfonylmethane (MSM) in Osteoarthritis

A study conducted on more than 100 patients on the combined therapy of glucosamine and MSM demonstrates its efficacy in the treatment of osteoarthritis joint pain.

By Lamberts Española.

Glucosamine is an effective chondroprotective agent, although its action in osteoarthritis is slow. On the other hand, Methylsulfonylmethane (MSM) is an effective analgesic and natural anti-inflammatory. In a study of 118 patients with mild or moderate osteoarthritis for 12 weeks, participants were randomly given the following treatments three times a day: 500 mg of glucosamine, 500 mg of MSM, 500 mg of glucosamine + 500 mg of MSM, placebo capsules

In the study it was observed that the combined glucosamine + MSM therapy was more effective in reducing pain and inflammation and in improving the functional capacity of the joints. The analgesic and anti-inflammatory activity of this combination was also faster than in the individual treatments, and did not present problems of intolerance (as in any of the other treatments).

Reference: Clin Drug Invest 2004; 24 (6): 353-363 Study available in our technical department.